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Thread: Jimmy Carter Says New Drug Made His Tumors Vanish

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    Jimmy Carter Says New Drug Made His Tumors Vanish

    -Jimmy Carter credits the new cancer drug Keytruda for shrinking his brain tumors completely. It's one more possible victory for the newest class of cancer drugs that empower the immune system to fight off tumors.

    But cancer experts note that it's not at all clear that the drug itself is what shrank Carter's tumors. The former president was also treated with radiation to his brain and had a large tumor on his liver removed.

    While most immune therapy drugs boost the immune system so that it can battle the cancer, Keytruda was the first drug to take a different approach that disrupts a trick tumors use to hide from immune cells.

    Keytruda — known generically as pembrolizumab — targets the activity of genes called PD-1 and PD-L1. The interaction between the two genes lets some tumors escape detection and destruction by immune system cells.

    "It's as good of an outcome as someone with advanced melanoma can hope for."

    PD-1 stops immune cells from attacking normal healthy cells by mistake. Tumor cells make PD-L1 turn on PD-1 when immune cells approach. Keytruda, an engineered immune protein called a monoclonal antibody, disrupts this cloaking effect and lets the immune cells do their job and eat the tumor cell.

    Carter's Sunday school class erupted in applause when he announced his latest checkup showed his tumors appear to have shrunk completely. "And when I went this week, they didn't find any cancer at all, so I have good news," he told his overflowing class...

    http://www.nbcnews.com/health/cancer...tumors-n475561

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    Senior Member Colonel's Avatar
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    Drugs that help the body fight the cancer. That is something different from the usual approach of applying destruction then hoping that it will destroy the cancer more than it destroys the rest of the body.

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    I wonder if it targets cancer stem cells, which is the absolute most important thing when someone is in remission. If he didn't change his diet or lifestyle at all, the stem cells can turn into cancerous cells very quickly. I also wonder if this drug has any devastating side effects. Many of the new immune therapy drugs also have very dangerous, severe, side effects.

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    Super Moderator Quest's Avatar
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    Quote Originally Posted by CatchyUsername View Post
    I wonder if it targets cancer stem cells, which is the absolute most important thing when someone is in remission. If he didn't change his diet or lifestyle at all, the stem cells can turn into cancerous cells very quickly. I also wonder if this drug has any devastating side effects. Many of the new immune therapy drugs also have very dangerous, severe, side effects.
    I guess anything that does not just boost the God designed process of healing has some significant risks..If you research this be sure to post your findings..

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    FaithfulOne (12-08-2015)

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    Well, they advertise one "immune therapy" drug on tv, and it does come with tons of side effects (one listed as, "death"). Also, Chris Wark from ChrisBeatCancer.com did a video on these drugs:



    Quote Originally Posted by Quest View Post
    I guess anything that does not just boost the God designed process of healing has some significant risks..If you research this be sure to post your findings..

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